Located in the Alaskan interior, Nenana is 55 road miles southwest of Fairbanks on the Parks Highway and 304 road miles northeast of Anchorage. It is situated on the south bank of the Tanana river, just east of the mouth of the Nenana River. Every winter, there will be a Tripod placed on the frozen river and people will wager on when the ice goes out enough to move the tripod. This is called the Nenana Ice Classic.